Dino Morea was born in Bangalore to an Italian father and an Anglo-Indian mother. He is the second of three brothers. Nicolo Morea is his older brother, and Santino Morea is his younger brother. His family moved to Bangalore, Karnataka in 1996. He attended and graduated from St. Josephs College in Bangalore and also went to Bangalore Military School. He was first noticed when he was modeling for a fashion company, and he soon received his first film offer.
Morea made his acting debut in Pyaar Mein Kabhi Kabhi opposite Rinke Khanna, which was a flop, but he got his breakthrough roles with Rajiv Menon's Tamil film Kandukondain Kandukondain, the 2002 horror film Raaz and the thriller, Gunaah. His other prominent films include, Baaz: A Bird in Danger, Sssshhh..., Rakht and Acid Factory. He is contestant of reality show Fear Factor – Khatron Ke Khiladi Level 3 in 2010.